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As a stress-inducible immunometabolic node, the IRG1/itaconate axis activates NRF2, suppresses the NLRP3 inflammasome and several programmed cell death pathways, including ferroptosis, necroptosis, and pyroptosis, and in certain contexts enhances TFEB-mediated autophagy and mitochondrial quality control
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This post is intended to give you a clear, grounded overview of peptides, the current regulatory environment, and three of the peptides receiving the most attention in integrative medicine today